Neil Sengupta, MD

  • Associate Professor of Medicine
  • Clinical Interests: Colon Cancer Prevention, Diverticular Diseases, Esophageal Diseases, Fatty Liver Disease, Gastroesophageal Reflux Disease, Gastrointestinal Bleeding, Peptic Ulcer Disease
  • Websites: Research Network Profile
  • Contact: nsengupta@uchicago.edu

Neil Sengupta, MD, is a general gastroenterologist and Associate Professor of Medicine at the University of Chicago. He sees patients with a wide range of digestive symptoms and diseases, including gastroesophageal reflux disease, peptic ulcer disease, gastrointestinal bleeding, and diverticular diseases.



Dr. Sengupta is a national expert in the management of gastrointestinal bleeding. He is the primary author for national clinical guidelines on the management of lower gastrointestinal bleeding, and has specific interests in the management of gastrointestinal bleeding while on antithrombotic medications and optimal diagnostic testing for hospitalized patients with gastrointestinal bleeding.



In addition, he serves as the GI section quality improvement director, and has active projects focused on improving the quality of colorectal cancer screening. Examples of initiatives undertaken have included the implementation of digital navigation for patients scheduled for colonoscopy, evaluating the use of computer-aided polyp detection, recruitment of patients into national clinical trials evaluating performance of blood based colorectal cancer screening tests, and video-based assessment of colonoscopy and polypectomy competency.



Dr. Sengupta also is a dedicated educator, teaching medical students, residents and fellows about gastrointestinal pathophysiology, performance of endoscopy, and clinical gastroenterology.

Beth Israel Deaconess Medical Center
Boston, MA
- Fellowship in Gastroenterology and Hepatology
2015

University of Pennsylvania
Philadelphia, PA
- Residency in Internal Medicine
2012

Common interventional procedures for chronic non-cancer spine pain: a systematic review and network meta-analysis of randomised trials.
Common interventional procedures for chronic non-cancer spine pain: a systematic review and network meta-analysis of randomised trials. BMJ. 2025 Feb 19; 388:e079971.
PMID: 39971346

Quality Indicators for Upper GI Endoscopy.
Quality Indicators for Upper GI Endoscopy. Am J Gastroenterol. 2025 Feb 01; 120(2):290-312.
PMID: 39808581

Creating a standardized tool for the evaluation and comparison of artificial intelligence-based computer-aided detection programs in colonoscopy: a modified Delphi approach.
Creating a standardized tool for the evaluation and comparison of artificial intelligence-based computer-aided detection programs in colonoscopy: a modified Delphi approach. Gastrointest Endosc. 2024 Nov 26.
PMID: 39608592

Quality indicators for upper GI endoscopy.
Quality indicators for upper GI endoscopy. Gastrointest Endosc. 2025 Feb; 101(2):236-260.
PMID: 39545899

Factors affecting Family Physician follow-up 30 days post-discharge from a Canadian Academic Emergency Department.
Factors affecting Family Physician follow-up 30 days post-discharge from a Canadian Academic Emergency Department. Ann Fam Med. 2024 Nov 01; 21(Suppl 3).
PMID: 38271161

The Role of Imaging for GI Bleeding: ACG and SAR Consensus Recommendations.
The Role of Imaging for GI Bleeding: ACG and SAR Consensus Recommendations. Radiology. 2024 03; 310(3):e232298.
PMID: 38441091

The Role of Imaging for Gastrointestinal Bleeding: Consensus Recommendations From the American College of Gastroenterology and Society of Abdominal Radiology.
The Role of Imaging for Gastrointestinal Bleeding: Consensus Recommendations From the American College of Gastroenterology and Society of Abdominal Radiology. Am J Gastroenterol. 2024 03 01; 119(3):438-449.
PMID: 38857483

Management of Lower Gastrointestinal Bleeding.
Management of Lower Gastrointestinal Bleeding. Am J Gastroenterol. 2024 01 01; 119(1):10-14.
PMID: 37725688

Computer-aided polyp detection (CADe) in real life: not the "CADe-llac" we were promised.
Computer-aided polyp detection (CADe) in real life: not the "CADe-llac" we were promised. Gastrointest Endosc. 2023 07; 98(1):110-112.
PMID: 37331763

Dual-Energy CT Evaluation of Gastrointestinal Bleeding.
Dual-Energy CT Evaluation of Gastrointestinal Bleeding. Radiographics. 2023 06; 43(6):e220192.
PMID: 37167088

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