Uzma D. Siddiqui, MD

  • Professor of Medicine
  • Clinical Interests: Barretts Esophagus, Esophageal Cancer, Gastrointestinal cancer risk and prevention, Gastrointestinal Cancers, Palliative Cancer Care, Pancreatic Cancer
  • Websites: Research Network Profile

Uzma Siddiqui, MD, is a gastroenterologist with expertise in interventional endoscopy. She is a Professor of Medicine and the Director of the Center for Endoscopic Research and Therapeutics (CERT). Her training includes fellowships in both gastroenterology and advanced endoscopy. Her practice focuses on specialized interventional endoscopy procedures, such as endoscopic ultrasound (EUS),endoscopic retrograde cholangiopancreatography (ERCP), and advanced tissue resection within the gastrointestinal tract.

EUS is a minimally invasive procedure used to diagnose and manage a wide range of gastrointestinal cancersand pre-cancerous lesions, including pancreatic tumors. Other therapeutic endoscopic procedures Dr. Siddiqui performs include endoscopic retrograde cholangiopancreatography (ERCP) with removal of stones and stenting of tumors to relieve obstruction in both the bile and pancreatic ducts, drainage of pancreatic cysts, nerve block for pain related to pancreatic cancer, ablation of Barrett's esophagus, endoscopic mucosal resection (EMR) and endoscopic submucosal dissection (ESD) of large polyps or small tumors in the GI tract, and treatment of swallowing disorders such as Zenker’s diverticulum and achalasia with per oral endoscopy myotomy (POEM).

A dedicated educator and mentor, Dr. Siddiqui teaches techniques of therapeutic endoscopy in courses for gastroenterologists, trainees, and nurses around the country and internationally. She is also a prominent researcher, focusing on improving the various applications of advanced endoscopic techniques with >100 publications and chapters in peer-reviewed journals. Dr. Siddiqui has received numerous honors over her career, including the 2019 Helio Woman Disruptor of the Year Award and the 2023 American Society for Gastrointestinal Endoscopy (ASGE) Master Endoscopist Award.

High Diagnostic Yield of Fine Needle Biopsy for Pancreatic Serous Cystadenomas-A Multicenter Study.
High Diagnostic Yield of Fine Needle Biopsy for Pancreatic Serous Cystadenomas-A Multicenter Study. Pancreas. 2025 Apr 01; 54(4):e349-e352.
PMID: 39626196

Large Single Center Comparison of Novel and Reusable Duodenoscopes Shows Similar Contamination Rates That Do Not Correlate With Clinical Infection.
Large Single Center Comparison of Novel and Reusable Duodenoscopes Shows Similar Contamination Rates That Do Not Correlate With Clinical Infection. Am J Gastroenterol. 2025 Feb 05.
PMID: 39907237

A rendezvous approach for ampullary access in a strictured duodenojejunostomy.
A rendezvous approach for ampullary access in a strictured duodenojejunostomy. VideoGIE. 2025 May; 10(5):250-252.
PMID: 40255627

Hemosuccus Pancreaticus From the Minor Papilla: A Rare Cause of Upper Gastrointestinal Bleed.
Hemosuccus Pancreaticus From the Minor Papilla: A Rare Cause of Upper Gastrointestinal Bleed. ACG Case Rep J. 2024 Sep; 11(9):e01510.
PMID: 39301460

North American Expert Consensus on the Post-procedural Care of Patients After Per-oral Endoscopic Myotomy Using a Delphi Process.
North American Expert Consensus on the Post-procedural Care of Patients After Per-oral Endoscopic Myotomy Using a Delphi Process. Clin Gastroenterol Hepatol. 2025 Apr; 23(5):776-784.
PMID: 39214390

Double Wire Cannulation and Mechanical Lithotripsy in Billroth II With Therapeutic Gastroscope.
Double Wire Cannulation and Mechanical Lithotripsy in Billroth II With Therapeutic Gastroscope. Clin Gastroenterol Hepatol. 2025 Feb; 23(2):A25-A26.
PMID: 39089522

Development of American Society for Gastrointestinal Endoscopy standards for training in advanced endoscopy within dedicated advanced endoscopy fellowship programs.
Development of American Society for Gastrointestinal Endoscopy standards for training in advanced endoscopy within dedicated advanced endoscopy fellowship programs. Gastrointest Endosc. 2025 Jan; 101(1):12-24.
PMID: 38935016

A multicenter, retrospective study of a through-the-needle injection-capable electrosurgical knife for endoscopic submucosal dissection.
A multicenter, retrospective study of a through-the-needle injection-capable electrosurgical knife for endoscopic submucosal dissection. Gastrointest Endosc. 2024 Dec; 100(6):1034-1042.
PMID: 38879045

Establishment of standards for the referral of large nonpedunculated colorectal polyps: an international expert consensus using a modified Delphi process.
Establishment of standards for the referral of large nonpedunculated colorectal polyps: an international expert consensus using a modified Delphi process. Gastrointest Endosc. 2024 Sep; 100(3):510-516.e6.
PMID: 38331224

Gender authorship in major American and European gastroenterology journals: the gap is still unfilled.
Gender authorship in major American and European gastroenterology journals: the gap is still unfilled. Endoscopy. 2024 Jun; 56(6):397-403.
PMID: 38325395

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